Thursday, April 5, 2012

Emery-Dreifuss Muscular Dystrophy (EDMD)

Onset:Usually by 10 years of age.
Symptoms:Weakness and wasting of shoulder, upper arm and calf muscles; joint stiffening; fainting (because of cardiac abnormalities).
Progression:Disease usually progresses slowly. Cardiac complications are common and sometimes require a pacemaker.
Inheritance:Can be X-linked recessive, primarily affecting males, who inherit the disease through their mothers. Another type is autosomal dominant, meaning it can be inherited through either parent; an autosomal-recessive type occurs when a faulty gene is inherited from each parent.

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